Analysis of GAS-6/AXL-L (Human) by MSD Hypersensitive Multi-Factor Electrochemiluminescence Analyzer (CAT#: STEM-MB-0198-LGZ)

Introduction

Gas6 (Growth arrest-specific protein 6) is a vitamin K-dependent protein that was first discovered in mouse embryonic fibroblasts in 1988, and its biological function is mediated by interacting with TAM receptors. Gas6/Axl is highly expressed in a variety of tumor tissues, and the activation of Axl in the Gas6/Axl signal is Axl dimerization and autophosphorylation induced by the ligand Gas6.

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Principle Applications Procedure Materials Notes Related Products

Principle

MSD electrochemiluminescence technology is mainly based on ultra-sensitive multi-factor electrochemiluminescence analyzer MES0 Sector600 or Quickplex SQ120. Through dot matrix technology, the detection of 10 indicators per well can be realized in the 96-hole graphite electrode plate. It can also be customized to realize the screening detection of 100 index wells in a 24-well plate.

Applications

Cardiac Biomarkers, Cardiovascular

Procedure

1. Coat the capture antibody on the well plate.
2. Add samples/calibrators.
3. Add detection antibody.
4. Read the plate and analyze the data.

Materials

• Sample Type: Plasma, Serum

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