Analysis of IL-28B/IFN-λ3 (Human) by MSD Hypersensitive Multi-Factor Electrochemiluminescence Analyzer (CAT#: STEM-MB-0337-LGZ)

Introduction

Interferon (IFN) receptor proteins are a class of cytokines secreted by host cells that regulate immune responses. The first cytokine to be discovered, it was named "interferon" because of the protein's ability to interfere with viral replication. When a pathogen is present, interferon is usually released by the host cell, which is sensed by surrounding uninfected cells and activates the appropriate cellular defense mechanisms in order to eliminate the pathogen.
IL-28B is also called IFNλ3. Human IL-28B gene encodes 200 amino acids including a 25 amino acid signal peptide and a mature protein with 175 amino acids lacking N-glycosylation sites.