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Lead (Pb) is a heavy metal belonging to period IV of the periodic table. This element is grey in color, malleable, soft, and can be extracted from the mineral galena (PbS). Widespread use of Pb, causing this element to be a pollutant to the environment and harmful to human health. Pb can enter the body through the digestive tract, breathing, and skin. Pb entering through the gastrointestinal tract will be distributed to bone (60%), liver (25%), kidney (4%), reticuloendothelial system (3%), intestinal wall (3%), and to other tissues. The accumulation of Pb in these organs can result in various organ disorders, such as impaired kidney function, cardiovascular, liver, brain, and hematopoietic system.