Analysis of LOC110121229 Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-1588-LGZ)

Introduction

Gene description: VISTA enhancer hs1945<br />Gene type: biological region<br />This locus represents a conserved genomic element that can function as an enhancer. The major subregion can activate a Hsp68 promoter coupled to a LacZ reporter gene in embryonic heart of transgenic mice. Two subregions were also shown to be active enhancers by ChIP-STARR-seq in human embryonic stem cells, where both are associated with the OCT4 and NANOG transcription factors and marked by the H3K27ac histone modification.