Analysis of membrane proteins by Circular dichroism (CD) (CAT#: STEM-MB-0598-WXH)

Introduction

Membrane proteins play essential roles in a wide variety of physiological functions, such as ionic regulation, molecular recognition, energy transduction and cell adhesion. It has been estimated that approximately 30% of all open reading frames in the human genome are membrane proteins and that they represent more than 60% of current drug targets. CD spectroscopy has special relevance for the study of membrane proteins, which are difficult to crystallise and largely ignored in structural genomics projects.