Analysis of RYR2 Gene (Mutation) in Primary Familial Hypertrophic Cardiomyopathy by RT-qPCR (CAT#: STEM-MT-0192-LGZ)

Introduction

Also known as: RyR; ARVC2; ARVD2; RYR-2; VTSIP; VACRDS<br />This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia.