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Official Full Name: succinate dehydrogenase complex subunit C<br />Also known as: CYBL; PGL3; QPS1; SDH3; CYB560<br />This gene encodes one of four nuclear-encoded subunits that make up succinate dehydrogenase, also known as mitochondrial complex II, a key enzyme complex of the mitochondrial tricarboxylic acid cycle and the aerobic respiratory chain. The encoded protein is one of two integral membrane proteins that anchor the other subunits of the complex forming the catalytic core to the inner mitochondrial membrane. This gene has several related pseudogenes on different chromosomes. Mutations in this gene are associated with paragangliomas. Alternative spliced transcript variants have been described.