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Official Full Name: sorting nexin 27
Also known as: MRT1; MY014
This gene encodes a member of the sorting connexin family, a group of distinct cytoplasmic and membrane-associated proteins involved in the endocytosis of plasma membrane receptors and the transport of proteins through these compartments. All members of this protein family contain a phosphoinosine-binding domain (PX domain). In mice, a highly similar protein is responsible for the specific recruitment of isoforms of the serotonin serotonin 4 receptor to early endosomes, suggesting a similar role for the human protein.