Unlock Exclusive Discounts & Flash Sales! Click Here to Join the Deals on Every Wednesday!
The protein encoded by the SPINK1 gene is a trypsin inhibitor secreted by pancreatic acinar cells into pancreatic juice. It is thought to play a role in preventing trypsin-catalyzed premature activation of zymogens in the pancreas and pancreatic ducts. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis.