Analysis of THEM4 Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-0695-LGZ)

Introduction

Official Full Name: thioesterase superfamily member 4<br />Also known as: CTMP<br />Protein kinase B (PKB) is a major downstream target of receptor tyrosine kinases that signal via phosphatidylinositol 3-kinase. Upon cell stimulation, PKB is translocated to the plasma membrane, where it is phosphorylated in the C-terminal regulatory domain. The protein encoded by this gene negatively regulates PKB activity by inhibiting phosphorylation. Transcription of this gene is commonly downregulated in glioblastomas.