Unlock Exclusive Discounts & Flash Sales! Click Here to Join the Deals on Every Wednesday!
Official Full Name: TNF receptor associated factor 5
Also known as: RNF84; MGC:39780
The scaffold protein encoded by this gene is a member of the tumor necrosis factor receptor-associated factor (TRAF) protein family, which contains a meprin and TRAF homology (MATH) domain, a ring-type zinc finger and two TRAF-type zinc fingers. TRAF proteins associate with members of the TNF receptor superfamily and mediate their signal transduction. This protein is part of a multiprotein complex that binds the cytoplasmic domain of the tumor necrosis factor (TNF) receptor and mediates TNF-induced activation. Multiple transcript variants encoding different isoforms have been found for this gene.