CMV (IE1) Peptide Pool, STEMCELL Technologies (CAT#: STEM-CT-0796-ZJF)

Stimulating T cells with CMV (IE-1) Peptide Pool releases downstream cytokines and upregulates activation markers, enabling antigen-specific T cells to be detected or isolated for analysis. CMV (IE-1) Peptide Pool is a lyophilized mixture of 120 peptides from the immediate early protein IE1 (IE1) of human cytomegalovirus (CMV; strain AD169), and consists of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 - 491 on IE1. CMV IE1 is a transcriptional transactivator and autoregulator (Cherrington & Mocarski). Studies show that IE1 promotes viral transcription by antagonizing histone deacetylation (Nevels et al.) and, along with IE2, may contribute to the survival of CMV-infected cells by blocking tumor necrosis factor alpha (TNF-α)-induced apoptosis (Zhu et al.). Viral peptide pools are useful for a broad range of applications, including vaccine development, immunological research, and diagnostic assay development.

Subtype: Peptide Pools
Species: Other
Application: Activation, Cell Culture
Area of Interest: Infectious Diseases
Purity: Average 70%

Reliable Consistency: Guarantees uniformity and repeatability in various applications with endotoxin levels below 0.2 EU/μg.
Free of Animal Components: Completely devoid of any animal or human-derived elements.
Broad Selection: Offers a wide range of human, mouse, and rat cytokines available in multiple sizes.

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