Detection of silk protein transitions by Differential Scanning Fluorimetry(DSF) (CAT#: STEM-MB-0754-WXH)

Introduction

Silk is made up of two primary proteins; a fibrous protein known as fibroin, and a sticky protein known as sericin, with the two comprising 70–80% and 20–30% of silk, respectively. Sericin has a high hydroxy amino acid content which is important for the water-binding capacity which regulates the skin's moisture content. It also has a unique carbohydrate moiety and a unique repetitive amino acid sequence which give it a high affinity for bonding to adhering proteins resulting in a tightening, anti-wrinkle effect. In addition, because of its high molecular weight, it leaves a substantive semi-occlusive film that persists even after washing, and can increase the skins permeability.