Human Recombinant FGF-8B, STEMCELL Technologies (CAT#: STEM-CT-0859-ZJF)

Fibroblast growth factor 8B (FGF-8B) is a member of the fibroblast growth factor (FGF) family and is an isoform of FGF-8. Cytokines in the FGF family possess broad mitogenic and cell survival activities (Folkman & Klagsbrun; Kimelman & Kirschner) and are involved in a variety of biological processes, including cell proliferation, differentiation, survival, and apoptosis (Folkman & Klagsbrun; Klagsbrun; Rifkin & Moscatelli). FGF-8B signals through FGF receptors (FGFRs) to activate PI3K and MAPK pathways. FGF-8B is broadly associated with mitogenic and cell survival activities, and regulates gastrulation, epithelial-mesenchymal transition, and later on mesenchymal to epithelial differentiation during embryonic development. FGF-8B has also been found in peripheral blood leukocytes and healthy bone marrow samples (Mattila & Härkönen). FGF-8B has mitogenic effects on somatic cells in the germinal epithelium and is expressed in adult mouse ovarian cells and tissues, which suggests that it regulates maturation of oocytes and seminiferous epithelium in testis (Valve et al.).

Subtype: Cytokines, Growth Factors
Alternatives Names: AIGF, Androgen-induced growth factor, FGF-8, FGF-8B, Fibroblast growth factor-8B, HBGF-8, Heparin-binding growth factor 8; HH6, KAL6
Cell Type: Endoderm, PSC-Derived, Hematopoietic Stem and Progenitor Cells, Neural Cells, PSC-Derived, Pluripotent Stem Cells
Species: Human
Area of Interest: Epithelial Cell Biology, Neuroscience, Stem Cell Biology
Molecular Weight: 22.5 kDa
Purity: > 95%

Reliable Consistency: Guarantees uniformity and repeatability in various applications with endotoxin levels below 0.2 EU/μg.
Free of Animal Components: Completely devoid of any animal or human-derived elements.
Broad Selection: Offers a wide range of human, mouse, and rat cytokines available in multiple sizes.

Human Recombinant FGF-7, ACF, STEMCELL Technologies
Human Recombinant FGF-8A, STEMCELL Technologies
Human/Mouse Recombinant FGF-8B, ACF, STEMCELL Technologies
Human Recombinant FGF-9, STEMCELL Technologies