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The mouse B7h3 gene was replaced by human B7H3 coding sequence in B-hB7-H3 EL4 cells. Human B7-H3 is highly expressed on the surface of B-hB7-H3 EL4 cells.
B-hB7-H3 EL4 cells have the capability to establish tumors in vivo and can be used for efficacy studies.
Common name: B-hB7-H3 EL4
Aliases: 4Ig-B7-H3, CD276, B7RP-2
Organism: Mouse
Tissue types: Lymphoma
Disease: Lymphoma
Strain: C57BL/6N
Tissue: T lymphocyte