Recombinant Human CD48 Protein, Seafrom (CAT#: STEM-CT-0137-ZJF)

The Recombinant Human CD48 Protein manufactured by Seafrom is suitable for immune cell interactions and responses.
CD48 antigen, also known as signaling lymphocyte activation molecule 2 (SLAMF2), SLAM family member 2, leukocyte antigen MEM-102, BCM1 surface antigen, and B-lymphocyte activation marker BLAST-1, is a 65 kDa GPI-linked protein. It belongs to the CD2 subfamily of molecules within the immunoglobulin superfamily. CD48 antigen comprises two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domains. CD48 interacts with CD244 in a heterophilic manner. CD48 serves as the ligand for CD2. It may facilitate interactions between activated lymphocytes and participate in the regulation of T-cell activation.
Storage information for lyophilized products: They can be stored at 4°C for 24 months, and the liquid after reconstitution can be stored at -20°C for 6-12 months, avoiding repeated freeze-thaw cycles.

Expression Host: Human HEK293 cells
Source: Human
Synonyms: BCM1, SLAMF2, BLAST, BLAST1, MEM-102, TCT.1, BCM-1, SLAMF-2, BLAST-1
Protein Sequence: The DNA sequence encodes human CD48 (GenBank: AAH16182.1), expressed with a His tag at the C-terminus.
Molecular Weight: Recombinant human CD48 protein contains 194 amino acids, with a predicted theoretical molecular weight of 24 kD.
Purity: ≥95%, confirmed by SDS-PAGE gel and high-performance liquid chromatography (HPLC) analysis.
Endotoxin: <0.1 EU/μg
Biological Activity: Immobilized human 2B4 (Fc tag) at a concentration of 2 μg/mL (100 μL/well) can bind to human CD48 (His tag) in a linear range of 0.2-2.0 μg/mL.
Purification Method: Chromatographic purification
Composition: Sterile PBS (pH 7.4) freeze-dried powder containing 6% mannitol.

Optimal Stability
Gmp-Grade Quality
Low Batch-to-Batch Variability
Exceptional Specificity
Robust Bioactivity
Efficient and Reliable Performance

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