Recombinant Human IFN-ω Protein, Seafrom (CAT#: STEM-CT-0045-ZJF)

The Recombinant Human IFN-ω Protein manufactured by Seafrom is suitable for antiviral activity and regulation of immune responses.
IFNs (Interferons) comprise a large family of proteins with antiviral, antiproliferative, and immunomodulatory effects. They are categorized into two main classes, type I and type II, based on differences in receptor binding and nucleotide sequence. Members of the type I interferon family, including IFN-α, IFN-β, and IFN-ω, signal through the IFNAR-1/IFNAR-2 receptor complex and exhibit antiviral and antiproliferative activities. Human IFN-ω was identified by three independent groups in 1985 and shares structural similarities with IFN-α and -β. Both human IFN-ω and IFN-α are produced by leukocytes induced by viral infections and display similar antiviral activities on human cell lines. IFN-ω shows approximately 75% sequence homology with IFN-α and contains two conserved disulfide bonds essential for its full biological activity. Furthermore, it has been reported that IFN-ω can inhibit the growth of human tumors in vivo.
The lyophilized product can be stored at 4°C for 24 months, and the reconstituted liquid can be stored at -20°C for 6-12 months, avoiding repeated freeze-thaw cycles.

Expression Host: Human HEK293 Cells
Synonyms: Human IFN-omega 1 Protein; Human IFNW1 Protein; Human interferon omega-1 Protein; IFN alpha II-1, IFNW1
Protein Sequence: Recombinant human IFN-ω protein with a His tag at the C-terminus, contains 194 amino acids, predicted molecular weight of 22.5 kD
Purity: ≥95%, analyzed by SDS-PAGE
Endotoxin Level: ≤0.05 EU/μg (gel clot method)
Purification Method: Chromatographic purification
Composition: Lyophilized powder in sterile PBS (pH 7.4) with 6% mannitol
Appearance: White loose body

Stable Cell Library
Large-Scale Expression
High Activity
Batch Stability
Gmp-Quality Control
Ensured Product Quality

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