The Recombinant Human Rantes (CCL5) Protein manufactured by Seafrom is suitable for studying chemotaxis and inflammation in immune responses. RANTES is a CC chemokine that signals through CCR1, CCR3, CCR5, and US28 (cytomegalovirus receptor). It acts as a chemoattractant for monocytes, memory T cells (CD4+/CD45RO), eosinophils, and basophils. RANTES also possesses the ability to inhibit certain strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The lyophilized form can be stored at 4°C for 24 months, while the reconstituted liquid can be stored at -20°C for 6-12 months, avoiding repeated freeze-thaw cycles.
Specification
Expression Host: Human HEK293 Cells Synonyms: D17S136E, eoCP, RANTES, SCYA5, SIS-delta, SISd, TCP228 Protein Sequence: DNA sequence encodes human CCL5 (NP_002976.2) with an Fc tag at the C-terminus, contains 306 amino acids, predicted molecular weight of 34.8 kD Purity: ≥95%, analyzed by SDS-PAGE and HPLC Endotoxin Level: ≤0.01 EU/μg (gel clot method) Biological Activity: Chemoattractant ability on human blood monocytes determined in a concentration range of 1.0-10.0 ng/mL Purification Method: Chromatographic purification
Features
Stable Cell Library Large-Scale Expression High Activity Batch Stability Gmp-Quality Control Ensured Product Quality
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