Recombinant Human Vimentin Protein, Seafrom (CAT#: STEM-CT-0063-ZJF)

The Recombinant Human Vimentin Protein manufactured by Seafrom is suitable for studying cell structure, migration, and wound healing.
Vimentin is a type III intermediate filament protein primarily found in cells of mesenchymal origin, such as vascular endothelial cells and blood cells. It is a major component of the cell's cytoskeleton. Vimentin is often used as a developmental marker for cells derived from mesenchyme or epithelial-to-mesenchymal transition cells due to its significance and abundance in the cytoskeletal structure of mesenchymal cells. It can undergo changes during normal growth and during processes like metastasis.
Vimentin plays an active role in various cellular processes, including anchoring organelles during apoptosis, development of astrocytes, and disassembly of cell components. Abnormalities in the normal physiological pathways of vimentin are associated with wound healing, cell growth and development, and the aggregation of vimentin adhesion sites in the lens epithelial cells of dominant cataracts.
The lyophilized formulation can be stored at 4°C for 24 months. Once reconstituted, the liquid can be stored at -20°C for 6-12 months, while avoiding repeated freeze-thaw cycles.

Expression Host: HEK293 Cells
Synonyms: CTRCT30, HEL113, Vim
Protein Sequence: DNA sequence encodes human Vimentin (NP_003371.2) with a His tag at the C-terminus, contains 471 amino acids, predicted molecular weight of 55 kD
Purity: ≥95%, analyzed by SDS-PAGE and HPLC
Endotoxin Level: ≤0.01 EU/μg (gel clot method)
Purification Method: Chromatographic purification

Stable Cell Library
Large-Scale Expression
High Activity
Batch Stability
Gmp-Quality Control
Ensured Product Quality

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