Single-Cell Culture

Single-cell cultivation is one of the most important processes in cellular and subcellular analysis, which allows the analysis of the heterogeneity of individual cells and provides sufficient single-cell clones and cell-derived products for further analysis.

Microfluidic Single-Cell Culture

Microfluidic devices are a useful tool for single-cell culture because they allow for precise control of the microenvironment for cell growth and real-time monitoring of cell behavior. Microfluidic cell culture allows controlling flow of culture medium and growth factors in the micrometer and nanoliter scale in precisely defined geometries and facilitates simultaneous manipulation and analysis starting from a single cell level, to larger cell populations and up to tissues cultured on fully integrated and automated chips. A multitude of individually controllable cell culture chambers assembled on a single chip facilitate high throughput and reproducible single cell culture.

Advantages of Microfluidic Single-Cell Culture

• Reduced reagent consumption
• Increased throughput
• Precise control of cell culture conditions
• Standardized manipulation, monitoring and sampling of cultured cells
• High automation without manual intervention
• Excellent live cell imagining
• Ability of combination of single-cell culture and downstream analysis
• Good cell activity after resuscitation

What We Can Do for You

• Cell coculture
• Cell regeneration
• Measurement of growth rates of individual cells
• Quantification of cellular responses to internal or external stimuli during cell culture periods on a single cell level
• Analysis of stem cells differentiation

For more information about our single-cell culture service, please contact us.