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Study of Bismuth silicone oxide (BSO) crystals by Raman Spectroscopy (CAT#: STEM-ST-0056-WXH)

Introduction

Bismuth silicone oxide (Bi12SiO20, BSO) crystals are highly efficient photoconductors with a low dark conductivity, that allows a build-up of large photo-induced space-charges. Tremendous photoconductivity and electro-optic properties make BSO crystals attractive in a range of applications: spatial light modulators, optical switches, phase conjugation mixers. BSO crystals are grown by modified Czochralski method and available in up to 3‘‘ diameter aperture size.




Principle

Raman Spectroscopy is a non-destructive chemical analysis technique which provides detailed information about chemical structure, phase and polymorphy, crystallinity and molecular interactions.
The principle behind Raman spectroscopy is that the monochromatic radiation is passed through the sample such that the radiation may get reflected, absorbed, or scattered. The scattered photons have a different frequency from the incident photon as the vibration and rotational property vary.

Applications

• Analysis of biocompatibility of a material.
• Analysis of nucleic acids.
• Study of interactions between drugs and cells.
• Photodynamic therapy (PDT).
• Analyzing metabolic accumulations of a substance or compounds.
• Diagnosis of disease.
• Analysis of individual cells.
• Cell sorting applications.
• Analyzing the features of biomolecules.
• Study of bone structure.

Procedure

1. Preparation of samples
2. Determine instrument parameters
3. Perform background scan
4. Test the sample
5. Data analysis

Materials

• Raman Spectrometer
• Raman Imaging Microscope
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