Study of Nuclear Protein Dynamics in Living Cells by Fluorescence recovery after photobleaching (FRAP) (CAT#: STEM-MT-0021-WXH)

Introduction

A nuclear protein is a protein found in the cell nucleus. Proteins are transported inside the nucleus with the help of the nuclear pore complex, which acts a barrier between cytoplasm and nuclear membrane. The import and export of proteins through the nuclear pore complex plays a fundamental role in gene regulation and other biological functions.
Proteins involved in chromatin-interacting processes, like gene transcription, DNA replication, and DNA repair, bind directly or indirectly to DNA, leading to their immobilisation.