Agilent 6470A LC/MS System, Agilent Technologies (CAT#: STEM-MS-0113-LGZ)

The manufacturer of Agilent 6470A LC/MS System is Agilent Technologies. Model is Agilent 6470A. The system is equipped with new ion optics, collision cells and detectors for increased sensitivity. The workstation provides a fast, reliable solution for the simultaneous quantification, screening and confirmation of analytes in the laboratory.

Condition: used
MRM sensitivity Signal-to-Noise ratio (S/N)
ESI positive
Measure: 1 pg of reserpine injected on column, quantifying on the transition m/z 609 to 195
Specification: S/N > 75,000:1 Noise 1 × RMS
MRM sensitivity Signal-to-Noise ratio (S/N)
ESI Negative
Measure: 1 pg of chloramphenicol injected on column, quantifying on the transition m/z 321 to 152
Specification: S/N > 30,000:1 Noise 1 × RMS
MRM sensitivity Instrument Detection Limit (IDL)
ESI positive
Measure: 10 fg of reserpine injected on column, quantifying on the transition m/z 609 to 195
Specification: IDL < 4.0 fg
MRM sensitivity Instrument Detection Limit (IDL)
ESI Negative
Measure: 10 fg of chloramphenicol injected on column,
quantifying on the transition m/z 321 to 152
Specification: IDL < 4.0 fg
Mass range
Specification: m/z 5–3,000
Polarity switching
Specification: 25 ms
Mass resolution (autotune)
Mass resolution (manual tune)
Measure: Full width at half maximum
Full width at half maximum
Specification: 0.7 Da
0.5 Da
Mass accuracy
Specification：
0.14 Da for m/z 5–999
0.20 Da for m/z 1,000–1,999
0.30 Da for m/z 2,000–3,000
Mass stability
Specification: ~ 0.1 Da in 24 hours
Dynamic range
Specification: > 6.0 × 106
Scan modes
Specification: MRM, SIM, MS scan, product ion scan, neutral loss/gain scan, and precursor ion scan
MRM transitions
Specification: 450 per time segment
Up to 13,500 MRM transitions per method
Dynamic MRM transitions
Specification: Up to 4,000 dynamic MRM transitions per method
Triggered MRM transitions
Specification:
Up to 10 MRM transitions (primary and secondary) per analyte for library search and compound confirmation
Maximum scan rate
Specification: 17,000 Da/s
Maximum MRM acquisition rate
Specification: 500 MRMs/s
Minimum MRM dwell time
Specification: 0.5 ms

1. Enhanced Sensitivity - Detection limit down to subflying figure level.
2. Stronger signal and lower noise - Agilent Jet Stream technology uses superheated nitrogen to improve ion generation and desolvation.
3. Compact design - reduces benchtop footprint.
4. Secure investment with flexible upgrades to Agilent iFunnel technology.
5. Efficient collection and transport of product ions from innovative curved and tapered hexapole assemblies.
6. Screening, Confirmation, and Quantitation - Triggered MRM (tMRM) combines fast, sensitive MRM quantification and generation of product ion spectra for library searching and compound screening and confirmation.

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