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Official Full Name: activating transcription factor 3<br />This gene encodes a member of the mammalian activator transcription factor/cAMP response element binding (CREB) protein family. The gene is induced by a variety of signals, including those encountered by many cancer cells, and is involved in the complex process of cellular stress responses. Multiple transcript variants of this gene have been found encoding different isoforms. Alternative splicing of this gene may have important physiological significance in the regulation of target genes.