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Official Full Name: CDC42 binding protein kinase alpha
Also known as: MRCK; MRCKA; PK428
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interacting binding (CRIB) domain and has been shown to bind CDC42. It may act as a downstream effector of CDC42, mediating CDC42-induced peripheral actin formation and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described.