Analysis of CHRM3 Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-0866-LGZ)

Introduction

Official Full Name: cholinergic receptor muscarinic 3<br />Also known as: HM3; PBS; EGBRS<br />Muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is determined by acetylcholine binding and includes cellular responses such as adenylyl cyclase inhibition, phosphocarnosine denaturation, and potassium channel mediation. Muscarinic receptors influence many of the actions of acetylcholine in the central and peripheral nervous systems. Muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion from glandular tissue. Different promoter usage and different splicing lead to multiple transcript variants with different tissue specificities.