Unlock Exclusive Discounts & Flash Sales! Click Here to Join the Deals on Every Wednesday!
Connective tissue growth factor (CTGF) is a cell matrix protein in the CNN family. The extracellular portion of CTGF consists of four conserved cysteine-rich domains: insulin-like growth factor binding protein (IGFBP), von Willebrand type C repeat (vWC), thrombocystein-type 1 repeat (TSR), and cysteine-containing C-terminal domain (CT). CTGF plays an important role in many biological processes, including cell adhesion, migration, proliferation, angiogenesis, bone development, and tissue wound repair. Monitoring serum levels of CTGF can provide more detailed insight into pathologic conditions such as malignant neoplasms, diabetic nephropathy, retinopathy, fibrosis, arthritis, pancreatic cancer and cardiovascular disease.