Analysis of dopaminergic antinociceptive actions on substantia gelatinosa neurons in the spinal cord by Patch clamp (CAT#: STEM-PET-0066-WXH)

Introduction

Dopamine (DA) is well known as a neurotransmitter and neuromodulator in the brain, not just as a precursor in the synthesis of other catecholamines. DA controls a variety of functions including locomotors activity, cognition, emotion, positive reinforcement, food intake, and endocrine regulation.
The substantia gelatinosa of Rolando (SGR) is a grey matter structure of the dorsal spinal cord primarily involved in the transmission and modulation of pain, temperature, and touch.