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Fibroblast activation protein, alpha (FAP-alpha) is a serine proteolytic enzyme with post-prolyl dipeptidyl peptidase activity and endopeptidase activity, and is activated by cleavage at the amino-terminal Xaa-Pro sequence. Involved in extracellular matrix degradation and involved in a variety of cellular processes including tissue remodeling, fibrosis, wound healing, inflammation and tumor growth.