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Official Full Name: Fc receptor like 4
Also known as: FCRH4; IGFP2; IRTA1; CD307d
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain, which contains three tyrosine-based immunoreceptor inhibitory motifs. This protein may play a role in the function of epithelial memory B cells. Aberrations in the chromosomal region encoding this gene have been linked to non-Hodgkin's lymphoma and multiple myeloma.