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Granulocyte colony stimulating factor (G-CSF) is a glycoprotein containing 174 amino acids with a molecular weight of about 20,000. G-CSF mainly acts on the proliferation, differentiation and activation of lineage hematopoietic cells. Clinically, G-CSF is mainly used for the prevention and treatment of leukopenia caused by radiotherapy or chemotherapy, the treatment of myelopoietic dysfunction and myelodysplastic syndrome, the prevention of potential infectious complications of leukopenia, and to accelerate the recovery of neutropenia caused by infection.