Analysis of HCC-4/CCL16 (Human) by MSD Hypersensitive Multi-Factor Electrochemiluminescence Analyzer (CAT#: STEM-MB-0241-LGZ)

Introduction

CCL16, also known as CC chemokine 4, liver expression chemokine (LEC) and monotactin-1 (MTN-1), is a small cytokine in the CC chemokine family and a group of chemokines located on human chromosome 17. CCL16 is also a ligand for the histamine H4 receptor. CCL16 chemotaxis monocytes and lymphocytes, but not neutrophils. Recent studies have shown that CCL16 increases tumor rejection, macrophage antigen presentation, and angiogenic activity of vascular endothelial cells. On the other hand, CCL16 may also enhance the anticancer effects of cytotoxic T cells and dendritic cell (DC) lymphocytes.