Analysis of IL19 Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-1070-LGZ)

Introduction

Official Full Name: interleukin 19
Also known as: MDA1; NG.1; ZMDA1; IL-10C
The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine was found to be preferentially expressed in monocytes. It can bind the IL-20 receptor complex and lead to the activation of signal transducer and activator of transcription 3 (STAT3). A similar cytokine has been reported to upregulate IL-6 and TNF-α expression and induce apoptosis in mice, suggesting a role for this cytokine in the inflammatory response. Alternative splicing transcript variants encoding different isoforms have been described.