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Official Full Name: integrin subunit alpha 10
Also known as: PRO827
Integrins are complete transmembrane glycoproteins composed of non-covalently linked alpha and beta chains. They are involved in cell adhesion as well as cell surface mediated signaling. This gene encodes the integrin α chain, is expressed at a high level in chondrocytes, and is transcriptionally regulated by AP-2epsilon and Ets-1 in chondrocytes. The protein encoded by this gene binds to collagen. Alternative splicing results in multiple transcript variants.