Analysis of LOC111501790 Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-1584-LGZ)

Introduction

Gene description: NFE2L2 motif-containing MPRA enhancer 30
Gene type: biological region
This genomic region was predicted to be a cell type-specific enhancer based on chromatin state analysis from the ENCODE (ENCyclopedia Of DNA Elements) project. It was validated as a functional enhancer by high-throughput massively parallel reporter assays (MPRAs) in both liver carcinoma HepG2 cells and erythroleukemia K562 cells. This enhancer contains a motif for the NFE2L2 activator. Mutation of this motif results in reduced enhancer activity.