Analysis of Mesothelin (Human) by MSD Hypersensitive Multi-Factor Electrochemiluminescence Analyzer (CAT#: STEM-MB-0413-LGZ)

Introduction

Mesothelin is a kind of cell surface glycoprotein with a molecular weight of 40kDa, which is a biological marker of early pancreatic cancer and is highly expressed in various tumor tissues, as well as in normal pleura, pericardium and peritoneal mesothelin cells, so it is not a tumor-specific protein. The Mesothelin gene encodes a 69kDa precursor protein, which is processed into a 40kDa membrane-binding protein (Mesothelin) and a 31kDa shed fragment called megakarya cell-promoting factor (MPF) and released extracellular, Mesothelin is recognized by monoclonal antibody (Mab) k1.