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Official Full Name: RNA polymerase I subunit A<br />Also known as: A190; RPA1; RPO14; AFDCIN; RPA190; RPA194; RPO1-4<br />The protein encoded by this gene is the largest subunit of the RNA polymerase I complex. The encoded protein represents the catalytic subunit of the complex, which transcribes DNA into ribosomal RNA precursors. Defects in this gene are a cause of the Cincinnati type of acrofacial dysostosis.