Analysis of RAGE (soluble) (Human) by MSD Hypersensitive Multi-Factor Electrochemiluminescence Analyzer (CAT#: STEM-MB-0516-LGZ)

Introduction

RAGE is a membrane protein that belongs to the immunoglobulin superfamily. It is highly homologous to MUC18 glycoprotein of the immunoglobulin superfamily, nerve cell adhesion molecule (NCAM), and the amino acid sequence of the intracellular part of CD20. Soluble RAGE(SRAGE), as the extracellular segment of RAGE, is a ligand-binding site with a V-type fragment followed by two C-type soluble immunoglobulin-like structures, each containing a pair of conserved cysteic acid residues, and soluble V-type soluble RAGE(SRage) contains two glycosylation sites coupled with N. These are important for the structural stability of RAGE and the function of specific recognition ligands.