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Official Full Name: serine and arginine rich splicing factor 7
Also known as: 9G8; AAG3; SFRS7
The protein encoded by this gene is a member of the serine/arginine-rich (SR)-rich pre-mRNA splicing factor family that forms part of the spliceosome. Each of these factors contains an N-terminal RNA recognition motif (RRM) for binding RNA and a C-terminal RS domain for binding other proteins. The RS domain is rich in serine and arginine residues that contribute to the interaction between different SR splicing factors. In addition to being essential for mRNA splicing, SR proteins have also been shown to be involved in mRNA export and translation from the nucleus. Multiple transcript variants of this gene have been found encoding different isoforms.