Analysis of TNFAIP6/TSG-6 (Human) by MSD Hypersensitive Multi-Factor Electrochemiluminescence Analyzer (CAT#: STEM-MB-0590-LGZ)

Introduction

Tumor necrosis factor alpha-inducible protein 6 (TNFAIP6), also known as TNF-stimulated gene 6 protein or TSG-6, is a protein encoded by the TNFaIP6 gene. It is a 30 kDa secreted protein containing a LINK domain a that binds hyaluronan and is thus a member of the hyaluronan-binding protein family, also known as hyaluronectin. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable covalent complex with inter-alpha inhibitor (IαI), thereby enhancing the serine protease inhibitory activity of IαI, which is important in protease networks associated with inflammation.