Analysis of Trypsin (TPO) by Raman Spectroscopy (CAT#: STEM-ST-0015-WXH)

Introduction

Trypsin (TPO) is produced by the exocrine cells of the mammalian pancreas. It is secreted as a proenzyme – trypsinogen, which is a part of the pancreatic juice. Trypsinogen (TGN) is converted to TPO by enterokinase, which is produced by the duodenal mucosal cells, and next TPO activates the other proteolytic enzymes. TGN activation within the pancreas is prevented by the presence of inhibitors that are also secreted by the acinar cells.With the autocatalytic ability of TPO there quickly occurs a full activation of separated TGN.