Capto S, 100 mL, Cytiva (CAT#: STEM-C-1552-LC)

Capto S manufactured by Cytiva is a strong cation exchanger for high-productivity and cost-effective capture and intermediate protein purification when high volume throughput is essential. It is composed of a rigid, high-flow agarose matrix modified with dextran surface extenders and a strong sulfonate (S) cation exchanger. Capto S features high volume throughput and high dynamic binding capacity to improve the productivity in industrial downstream processes. Capto S withstands effective and rigorous CIP procedure and the chemical stability supports long resin lifetime.

Chromatography technique: Ion Exchange Chromatography
BioProcess resin: Yes
Ligand: Sulfonate group
Particle size, d50V1: ~90 μm
Ion Exchanger Type: Strong cation exchanger
Matrix: Highly cross-linked agarose with dextran surface extender
Ligand Coupling Method: Dextran surface extenders
Ionic Capacity: 0.11-0.14 mmol Na+/ml medium
pH stability, operational2: 4-12
pH stability, CIP3: 3-14
Pressure/Flow Specification: 300 kPa at 700 cm/h, 1 m diameter column, 20 cm bed height
Storage: 4 to 30°C, 20% Ethanol + 0.2 M Sodium Acetate
Chemical stability: Commonly used aqueous buffers, 1 M acetic acid, 1 M NaOH, 8 M urea, 6 M guanidine hydrochloride, 30% isopropanol and 70% ethanol
Pack size: 100 mL

High dynamic binding capacity at high flow raises productivity
High-volume throughput cuts process times
Cost-effective processing with smaller unit operations
Durable and stable
Meets industrial demands for security of supply, robust performance, and regulatory support

MacroCap SP, 25 mL, Cytiva (CAT#: STEM-C-1578-LC)