Characterization of DNA-protein interaction by Nanoparticle tracking analysis (NTA) (CAT#: STEM-MB-0713-WXH)

Introduction

DNA Protein interactions play very vital roles in any living cell. It controls various cellular processes which are very essential for living beings, viz. replication, transcription, recombination, DNA repair etc. There are several types of proteins found in a cell.

Add to Cart Please Inquire

Principle Applications Procedure Materials Notes Related Products

Principle

Nanoparticle tracking analysis (NTA) is a method for visualizing and analyzing particles in liquids that relates the rate of Brownian motion to particle size. The rate of movement is related only to the viscosity and temperature of the liquid; it is not influenced by particle density or refractive index. NTA allows the determination of a size distribution profile of small particles with a diameter of approximately 10-1000 nanometers (nm) in liquid suspension.

Applications

NTA has been used by commercial, academic, and government laboratories working with nanoparticle toxicology, drug delivery, exosomes, microvesicles, bacterial membrane vesicles, and other small biological particles, virology and vaccine production, ecotoxicology, protein aggregation, orthopedic implants, inks and pigments, and nanobubbles.

Procedure

1. Sample preparation
2. Nanoparticle Tracking Analysis
3. NTA Data Processing, Display, and Interpretation

Materials

• Nanoparticle Tracking Analysis (NTA) instrument
• NanoSight instrument
• Nanoparticle Analyzer

Other recommended products

Characterization of cellular microvesicles by Nanoparticle tracking analysis (NTA) (CAT#: STEM-MB-0735-WXH)
Nanoparticle Tracking Analysis of β-Casein Nanocarriers by Nanoparticle tracking analysis (NTA) (CAT#: STEM-MB-0723-WXH)
Sizing and phenotyping of cellular vesicles by Nanoparticle tracking analysis (NTA) (CAT#: STEM-MB-0706-WXH)
Analysis of polymeric nanoparticles by Nanoparticle tracking analysis (NTA) (CAT#: STEM-MB-0734-WXH)
characterization of Proteinaceous Submicron Particles by Nanoparticle tracking analysis (NTA) (CAT#: STEM-MB-0710-WXH)
Analysis of Copper nanoparticles by Nanoparticle tracking analysis (NTA) (CAT#: STEM-MB-0747-WXH)
Investigation of Extracellular transport of NPs (nanoparticles) by Nanoparticle tracking analysis (NTA) (CAT#: STEM-MB-0748-WXH)
Detection of Membrane Receptor-Ligand Interactions by Nanoparticle tracking analysis (NTA) (CAT#: STEM-MB-0724-WXH)