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The precise size of nucleic acids fragments in the sample is key for many protocols used in a molecular and genetic laboratory - as quality control of DNA for gene panel testing, quality control of sequencing libraries, for PCR amplicon typing, RNA integrity, and degeneration monitoring. High-resolution fragment size determination also allows sensitive genotyping of insertions and deletions. Nucleic fragments sizing has an important role in other fields such as microbiology, biochemistry, forensic pathology or food processing industry.<br />Digital capillary electrophoresis can analyze up to 96 samples in one run without manual intervention and analysis of one to twelve samples takes only a few minutes depending on the chosen method and resolution. Due to digital processing and data analysis, no additional manipulation with gels and potentially dangerous chemicals during colouring, visualization and photographing of gels is needed. Hazardous waste handling is reduced as well.