Human Recombinant GDF-5, STEMCELL Technologies (CAT#: STEM-CT-0873-ZJF)

Growth differentiation factor 5 (GDF-5) is a member of the bone morphogenetic protein (BMP) subclass of the transforming growth factor beta (TGF-β) superfamily. It binds a receptor complex comprising BMPR1B and BMPR2, which then activates the SMAD signaling pathway (Carreira et al.; Nishitoh et al.; Osório et al.). GDF-5 enhances chondrogenic differentiation of mesenchymal stem cells, skeletogenesis, and dendrite growth during development (Coleman et al.; Francis-West et al.). Studies in rat demonstrated that GDF-5 regulates patterning, neurogenesis, astrogliogenesis, and neuronal specification (Gajavelli et al.; Krieglstein et al.; O’Keeffe et al.).

Subtype: Cytokines
Alternatives Names: BMP-14, Bone morphogenic protein 14, CDMP-1, Growth differentiation factor 5
Cell Type: Endoderm, PSC-Derived, Neural Stem and Progenitor Cells
Species: Human
Area of Interest: Neuroscience, Stem Cell Biology
Molecular Weight: 13.7 kDa monomer; 27.4 kDa dimer
Purity: ≥ 95%Subtype: Cytokines
Alternatives Names: BMP-14, Bone morphogenic protein 14, CDMP-1, Growth differentiation factor 5
Cell Type: Endoderm, PSC-Derived, Neural Stem and Progenitor Cells
Species: Human
Area of Interest: Neuroscience, Stem Cell Biology
Molecular Weight: 13.7 kDa monomer; 27.4 kDa dimer
Purity: ≥ 95%

Reliable Consistency: Guarantees uniformity and repeatability in various applications with endotoxin levels below 0.2 EU/μg.
Free of Animal Components: Completely devoid of any animal or human-derived elements.
Broad Selection: Offers a wide range of human, mouse, and rat cytokines available in multiple sizes.

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