Human Recombinant Lipocalin-2, STEMCELL Technologies (CAT#: STEM-CT-0771-ZJF)

Lipocalin-2 (LCN2) is a member of the lipocalin superfamily, which share a highly conserved fold containing an eight-stranded antiparallel beta barrel (Flower), and transport small hydrophobic molecules. Playing a role in innate immunity, Lipocalin-2 acts as a potent bacteriostatic reagent by sequestering iron-containing siderophores (Flo et al.). It is mainly expressed in activated neutrophils, but is also secreted by other immune cells in response to infection. Lipocalin-2 has been implicated in multiple cellular processes, such as differentiation (Yang et al.), migration (Du et al.), and apoptosis (Devireddy et al.). In vitro studies suggest that lipocalin-2 is a potential therapeutic target for certain cancers, including colorectal cancer (CRC; Zhang et al.) and chronic lymphocytic leukemia (Bauvois et al.). This protein product contains a His-residue tag at the carboxyl end of the polypeptide chain. For consistency and reproducibility across your applications, Lipocalin-2 from STEMCELL comes lyophilized with ≥ 94% purity, and endotoxin levels are verified to be ≤ 1.0 EU/μg protein.

Subtype: Cytokines
Alternatives Names: 24p3, MSFI, NGAL, p25
Species: Human
Area of Interest: Metabolism
Purity: ≥ 94%

Reliable Consistency: Guarantees uniformity and repeatability in various applications with endotoxin levels below 0.2 EU/μg.
Free of Animal Components: Completely devoid of any animal or human-derived elements.
Broad Selection: Offers a wide range of human, mouse, and rat cytokines available in multiple sizes.

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