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Clastrin-mediated endocytosis is a process by which cells bud inward through the plasma membrane (invagination) to absorb metabolites, hormones, proteins, and certain viruses. This process forms vesicles containing the absorbed substance and is strictly mediated by receptors on the cell surface. Only receptor-specific substances enter cells through this process.
Endocytic events on the plasma membrane of living cells can be imaged using stimulated emission reduction microscopy.
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