Measurement of Viscosity of Pediatric Liquid Analgesics Sweets by Rotating Viscometer Method (CAT#: STEM-PPA-0024-YJL)

Introduction

Pediatric liquid analgesics (PLA) are widely prescribed and are easily accepted by both parents and children. However, these drugs can place patients at risk for dental caries and dental erosion, especially when used on a regular basis and over a long period of time Sucrose is widely used in the pharmaceutical industry due to its properties as preservative, antioxidant, solvent and thickening agent.
The erosive potential of food of liquid preparations depends on pH, titratable acid, type of acid (pKa), calcium chelation properties and physical and chemical properties affecting adherence to the enamel surface and stimulation of salivary ﬂow. Liquid oral medicines are usually viscous syrups that penetrate into ﬁssures and proximal areas that are inaccessible to the toothbrush. Therefore, regular and long-term use of medications with prolonged oral clearance may increase the risk of dental caries if they contain sugars or dental erosion if they contain acids.

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Principle Applications Procedure Materials Notes Related Products

Principle

The principle of the rotating viscometer method to measure the force acting on a rotor (torque) when it rotates at a constant angular velocity (rotational speed) in a liquid. Rotating viscometers are used for measuring the viscosity of Newtonian (shear-independent viscosity) or non-Newtonian liquids (shear dependent viscosity or apparent viscosity). Rotating viscometers can be divided in 2 groups, namely absolute and relative viscometers. In absolute viscometers the flow in the measuring geometry is well defined.
The measurements result in absolute viscosity values, which can be compared with any other absolute values. In relative viscometers the flow in the measuring geometry is not defined. The measurements result in relative viscosity values, which cannot be compared with absolute values or other relative values if not determined by the same relative viscometer method. Different measuring systems are available for given viscosity ranges as well as several rotational speeds.

Applications

Mineral oil industry; Food industry; Cosmetic/pharmaceutical industry; Petroleum industry; Chemical industry

Procedure

1. Pour the liquid into the measuring cup.
2. Insert the spindle into the liquid.
3. Rotate the spindle and measure the resistance.

Materials

• Sample Type: liquid, gel-like, or semi-solid everyday substances

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