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Recombinant Human OX40 Protein, Seafrom (CAT#: STEM-CT-0098-ZJF)

Highlights

Optimal Stability
Gmp-Grade Quality
Low Batch-to-Batch Variability

Cat Number: STEM-CT-0098-ZJF

Application: For T-cell co-stimulation and immune responses.

Model: TL725

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Description

The Recombinant Human OX40 Protein manufactured by Seafrom is suitable for T-cell co-stimulation and immune responses.
Tumor necrosis factor receptor superfamily member 4 (TNFRSF4), also known as ACT35 antigen, OX40 ligand receptor, TAX transcriptionally-activated glycoprotein 1 receptor, CD antigen CD134, or simply OX40, is a protein that contains four TNFR-Cys repeats. TNFRSF4 acts as a receptor for TNFSF4 (OX40L/GP34) and is capable of interacting with signaling proteins like TRAF2, TRAF3, and TRAF5.
The lyophilized product can be stored at 4°C for 24 months. After reconstitution, the liquid can be stored at -20°C for 6-12 months, but avoid repeated freeze-thaw cycles.

Specification

Expression Host: Human HEK293 cells
Source: Human
Synonyms: TNFRSF4, CD134, OX40L receptor, ACT35, TXGP1L
Protein Sequence: The DNA sequence encodes human OX40 (NCBI Reference Sequence: NP_003318.1), expressed with a His tag at the C-terminus.
Molecular Weight: Recombinant human OX40 protein consists of 189 amino acids, with a predicted theoretical molecular weight of 21.8 kD.
Purity: ≥95%, confirmed by SDS-PAGE gel and high-performance liquid chromatography (HPLC) analysis.
Endotoxin: <0.1 EU/μg
Biological Activity: The linear range for binding of human OX40 (His tag) at 1μg/mL (100μL/well) to human OX40 Ligand (Fc tag) is 1-10 ng/mL.
Purification Method: Chromatographic purification
Composition: Sterile PBS (pH 7.4) freeze-dried powder containing 6% mannitol.

Features

Optimal Stability
Gmp-Grade Quality
Low Batch-to-Batch Variability
Exceptional Specificity
Robust Bioactivity
Efficient and Reliable Performance

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