Study of the function and reliability of microsystems by Raman Spectroscopy (CAT#: STEM-ST-0087-WXH)

Introduction

The microsystems field is growing very fast in the new millennium. This exponential growth goes together with an increasing demand for reliability assessment of microsystems. The reliability of a device is influenced by many
parameters during the whole cycle of its development: from the characteristics of the
materials used (thermo-mechanical, roughness, adhesion, etc.) to the environment where the device has to work (temperature cycles, vibrations, shock, etc.).

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Principle Applications Procedure Materials

Principle

Raman Spectroscopy is a non-destructive chemical analysis technique which provides detailed information about chemical structure, phase and polymorphy, crystallinity and molecular interactions.
The principle behind Raman spectroscopy is that the monochromatic radiation is passed through the sample such that the radiation may get reflected, absorbed, or scattered. The scattered photons have a different frequency from the incident photon as the vibration and rotational property vary.

Applications

• Analysis of biocompatibility of a material.
• Analysis of nucleic acids.
• Study of interactions between drugs and cells.
• Photodynamic therapy (PDT).
• Analyzing metabolic accumulations of a substance or compounds.
• Diagnosis of disease.
• Analysis of individual cells.
• Cell sorting applications.
• Analyzing the features of biomolecules.
• Study of bone structure.

Procedure

1. Preparation of samples
2. Determine instrument parameters
3. Perform background scan
4. Test the sample
5. Data analysis

Materials

• Raman Spectrometer
• Raman Imaging Microscope

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